Bone Abstracts

Pparβ is crucial for muscle fatty acid oxidation. Pparβ−/− mice have reduced muscle strength, exercise performance, and also a decreased skeletal response to exercise. Here we investigate the influence of Pparβ on muscle and bone loss with aging, and its role on the bone biomechanical response to loading. Pparβ−/− and Pparβ+/+ mice were monitored at 1, 3 and 18...